Pinealon Reference Guide

Compound Reference Overview

Field Value
Name Pinealon
Reference Code PIN
Category Cognitive / Pineal Bioregulator Peptide
Example Strength 10 mg vial (varies by manufacturer)
Reference Range 100–500 mcg daily (evening dosing typical)
Frequency Once daily
Key Safety Warning May increase melatonin activity and cause drowsiness. Dose in the evening. Not FDA-approved.

Mechanism of Action (Educational)

Pinealon is a synthetic tripeptide (Ala-Glu-Asp sequence) derived from pineal gland peptide extracts. It is part of the Khavinson peptide bioregulator series.

Experimental literature suggests Pinealon may modulate pineal gland function, support melatonin synthesis, and exert antioxidant and neuroprotective effects. It has been studied for its potential role in circadian rhythm regulation and age-associated cognitive decline.

Indications (Literature / Off-Label)

  • Sleep regulation
  • Neuroprotection research
  • Cognitive aging support
  • Circadian rhythm modulation

Administration (Literature)

Parameter Details
Route Subcutaneous
Frequency Once daily
Injection Sites Abdomen or thigh
Timing Evening, 1–2 hours before bedtime

Titration Schedule (Literature)

  • 100–200 mcg daily (initiation)
  • 200–500 mcg daily based on response
  • No formal escalation required

Evening dosing is recommended due to melatonin-related effects.

Pharmacokinetics (Literature)

  • Short systemic half-life (hours)
  • Sleep-related effects observed within days
  • Long-term neuroprotective effects remain investigational

Reconstitution & Concentration (Mathematical Illustration Only)

Parameter Value
Diluent Bacteriostatic water (example only)
Reconstitution Volume 2 mL (example)
Resulting Concentration 5 mg/mL (5000 mcg/mL)
Stability Up to 28 days refrigerated (varies by formulation)

Reconstitution Math Example

  • 10 mg ÷ 2 mL = 5 mg/mL
  • 0.02 mL = 100 mcg
  • 0.04 mL = 200 mcg
  • 0.10 mL = 500 mcg

Provided strictly for arithmetic reference.

Mathematical Calculation Tool

The calculator below allows concentration and volume calculations based on vial strength and dilution volume. This tool is provided strictly for mathematical reference.

Peptide Reconstitution Calculator

For Educational & Professional Reference Only

⚠️ This is a mathematical reference tool only. No medical or dosing advice is provided.

Safety & Contraindications (Summary)

Contraindications

  • Pregnancy or breastfeeding
  • Known hypersensitivity

Drug Interactions

  • Sedatives or hypnotics (mild additive effects)

Adverse Events

  • Drowsiness
  • Vivid dreams

Serious Risks

  • Rare in available literature

Monitoring (Literature)

  • Sleep quality
  • Cognitive function
  • Circadian rhythm patterns

Disclaimer

Pinealon is not FDA-approved. This content is provided strictly for educational and professional reference purposes. All clinical decisions must be made by a licensed healthcare professional.

Reference Sources