NA-Selank Reference Guide

Compound Reference Overview

Field Value
Name NA-Selank (N-Acetyl Selank)
Reference Code SELANK
Category Cognitive / Anxiolytic Peptide
Example Strength 10 mg vial (varies by manufacturer)
Reference Range 250–1000 mcg once daily
Frequency Once daily
Key Safety Warning Not FDA-approved. Limited large-scale human trials outside Russia. Use caution when combined with other anxiolytics.

Mechanism of Action (Educational)

NA-Selank is an N-acetylated synthetic analog of Selank, a heptapeptide derived from tuftsin. It modulates GABAergic signaling and influences serotonin and dopamine pathways.

Research suggests Selank may enhance brain-derived neurotrophic factor (BDNF) expression and regulate cytokine activity, contributing to anxiolytic and cognitive-enhancing effects without significant sedation.

Indications (Literature / Off-Label)

  • Anxiety and stress modulation
  • Cognitive enhancement
  • Learning and memory support
  • Stress-related cognitive impairment

Administration (Literature)

Parameter Details
Route Subcutaneous or intranasal
Frequency Once daily
Injection Sites Subcutaneous: abdomen
Intranasal: divided between nostrils
Timing Morning or as needed for anxiety; adjust based on fatigue response

Titration Schedule (Literature)

  • Weeks 1–2: 250–500 mcg once daily
  • Weeks 3+: 500–750 mcg daily based on response
  • Maximum commonly referenced range: 1000 mcg daily

Adjust timing if fatigue occurs.

Pharmacokinetics (Literature)

  • Rapid CNS activity observed (minutes to hours)
  • Anxiolytic effects reported within hours to days
  • Human pharmacokinetic data remain limited

Reconstitution & Concentration
(Mathematical Illustration Only)

Parameter Value
Diluent Bacteriostatic water (example only)
Reconstitution Volume 2 mL (example)
Resulting Concentration 5 mg/mL (5000 mcg/mL)
Stability Up to 28 days refrigerated (varies by formulation)

Reconstitution Math Example

  • 10 mg ÷ 2 mL = 5 mg/mL
  • 0.1 mL = 500 mcg
  • 0.2 mL = 1000 mcg

Provided strictly for arithmetic reference.

Mathematical Calculation Tool

The calculator below allows concentration and volume calculations based on vial strength and dilution volume. This tool is provided strictly for mathematical reference.

Peptide Reconstitution Calculator

For Educational & Professional Reference Only

⚠️ This is a mathematical reference tool only. No medical or dosing advice is provided.

Safety & Contraindications (Summary)

Contraindications

  • Pregnancy or breastfeeding
  • Known hypersensitivity

Drug Interactions

  • Benzodiazepines (moderate): additive anxiolytic effect

Adverse Events

  • Fatigue
  • Nasal irritation (intranasal use)
  • Headache

Serious Risks

  • Rare in available literature

Monitoring (Literature)

  • Anxiety levels
  • Mood changes
  • Cognitive performance

Disclaimer

NA-Selank is not FDA-approved. This content is provided strictly for educational and professional reference purposes. All clinical decisions must be made by a licensed healthcare professional.

Reference Sources